DATA RELEASES

Release: 2018.02 30 July 2018

  • Data
  • Website changes
    • Embryo DMDD IDs can be listed in the summary tables on the line pages.
    • Miscellaneous UX changes.
  • New content
    • New protocol pages added for mouse heart isolation, blood removal and embryo harvesting.
  • Allele nomenclature changes
    • Mir96tm2.2(IMPC)Wtsi renamed Mir96tm2.2Wtsi
    • Xbp1tm1a(EUCOMM)Wtsi/Ics renamed Xbp1tm1a(EUCOMM)Wtsi

Release: 2018.01 11 June 2018

  • Data
  • Website changes
    • MailChimp mailing forms removed.
    • Usersnap feedback form removed.
    • Ammended privacy policy.
    • Miscellaneous UX changes.
  • New content
    • Embryonic viability is reported at E9.5 and E14.5 for mutant lines.
    • Immunofluorescent and nissl stained images of the E18.5 nervous sytem (see Trappc9).
  • Gene nomenclature updates
    • Fam46c renamed Tent5c
    • 9130011E15Rik renamed Armh3
  • Allele nomenclature changes
    • Brd2em2Wtsi renamed Brd2em1(IMPC)Wtsi
    • Cfap53em2Wtsi renamed Cfap53em1(IMPC)Wtsi
    • Crim1em1Wtsi renamed Crim1em1(IMPC)Wtsi
    • Fut8em1Wtsi renamed Fut8em1(IMPC)Wtsi
    • Mir96Tm2.2WTSI renamed Mir96tm2.2(IMPC)Wtsi
  • Ontology
    • The Mammalian Phenotype Ontology has been updated to version 20180212.

Release: 2017.03 24 November 2017

  • Data
  • Website changes
    • Icons indicate annotated embryos in the stackviewer.
    • Improved print layout.
    • Miscellaneous UX changes.
  • New content
    • P14 viability is reported for mutant lines.
    • The Theiler stage of an embryo is listed where assessed.
    • The voxel size of each HREM image stack is shown.
    • 2000 additional images of the placenta and yolk sac show the distribution of E-Cadherin protein, Tpbpa RNA and Isolectin BSI-B4.
    • New page linking to reference wild-type atlases.

Release: 2017.02 14 July 2017

  • Data
  • Website changes
    • Interactive link to the Kaufman Atlas hosted at EMAP added on the stackviewer page.
    • Reorganisation of the line summary tables to generate E14.5 and E9.5 summaries.
  • New content
    • The sex of embryos determined by morphological and molecular techniques is reported.

Release: 2017.01 6 March 2017

  • Data
  • Nomenclature updated to reflect MGI status
    • Fam21 renamed Washc2.
  • Website changes
    • Search by anatomical term using mouse (EMAPA and MA) and human (EHDAA2 and FMA) ontologies
    • Search results now include early embryonic lethal genes
    • Search results now include genes not studied by DMDD, but with embryo data on the IMPC website
  • New content
    • New protocol page detailing phenotyping at E14.5
    • Page on gene expression profiling of mutant embryos, with initial 11 lines
    • Early lethals page with listing and download
    • Embryo phenotype annotations - listing and download

Release: 2016.04 30 November 2016

MAJOR WEBSITE REVISION

  • Font change
    • The body font was changed from serif to sans serif with improved letter spacing to make it easier to read.
  • News
    • News separated from releases, with images where relevant. The dedicated news page highlights new content on the website and the DMDD blog, upcoming events we'll be attending, and the DMDD social channels.
  • Homepage
    • Reduced the height of the page to make it easier to see all the content on laptop devices.
    • Made the background image on the homepage much larger and more of a feature, at the same time reducing file sizes of these random images.
    • Added 'ticker' text to the homepage, providing easily scannable bite size chunks about the DMDD programme, told in a logical 'story'.
    • Added search box to the homepage enabling users to easily search for genes or phenotypes, without having to click on a button in the navigation.
    • Added newsletter signup to the homepage to encourage users to signup to receive regular newsletter updates.
  • Navigation
    • Changed the global navigation menu at the top of the page to a 'mega menu' that provides users with more information about the sections of the website, to help ensure that where they end up is where they intended to be, and also makes it easier to discover other parts of the website.
  • New and revised content, especially:
    • About the DMDD programme
    • DMDD pipeline
    • About the mutants
    • Wild-type gene expression profiling
    • Research protocols added, as well as new section on HREM.
    • Communications materials page created with downloadable, shareable assets.
  • CSS styling review and tidy up
  • Embryo page
    • Removed accordion to make it more immediately apparent what data is available for each embryo at a glance (without multiple clicks).
  • Feedback link
    • Moved from RHS of all pages, where it was missed, to within the 'utilities' section at the top right of each page, where users expected to find it.
  • Added initial favicon.ico

Release: 2016.03 05 August 2016

Release: 2016.02 03 May 2016

Release: 2016.01 23 February 2016

Release: 2015.11 25 November 2015

Release: 2015.10 2 October 2015

  • Improved reporting of genotypes
    • Genotype shown rather than an abbreviation
    • Added a tooltip to the genotype abbreviation symbol where space constraints
  • Fixed the display of arrows on the search, embryo page and stackviewer help
  • Added links to programme partners
  • Updated the DMDD workflow diagram to change NIMR to the Crick

Release: 2015.09 18 August 2015

Release: 2015.08 1 July 2015

Release: 2015.07 18 May 2015

  • HREM image data for Psph
  • HREM annotation data for Prrc2b
  • Additional placenta data for Psph, Chop, Nek9, Vps33b
  • Symbol update: Jmjd5 is now a synonym of Kdm8
  • Added gene synonyms to the gene listing page and individual gene pages
  • Added icons to the gene listing page to indicate the availability of data for each gene
  • Added help tour to individual gene pages
  • Simplified search user interface

DMDD website launch April 2015

  • Modern new design for website
  • New interactive tools for viewing embryo data
  • Comprehensive search functions
  • Standardised phenotype data available
  • Summaries for mutant lines
  • Placenta images and phenotyping

Request data

All data is available to view on the DMDD website, and you can also request data for further study.