DMDD Crim1 report

Crim1^{em1(IMPC)Wtsi}

gene synonyms

LINE VIABILITY: Lethal

SHOW LINE PHENOTYPES

E18.5 neural data for line

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E14.5 -/- DMDD6401_3d movie still

DMDD6401_3d movie still

Ⓟ DMDD6401 data

E14.5 -/- DMDD6396_3d movie still

DMDD6396_3d movie still

DMDD6396 data

E14.5 -/- DMDD6388_3d movie still

DMDD6388_3d movie still

Ⓟ DMDD6388 data

E14.5 -/- DMDD6387_3d movie still

DMDD6387_3d movie still

DMDD6387 data

E14.5 -/- DMDD6384_3d movie still

DMDD6384_3d movie still

Ⓟ DMDD6384 data

E14.5 -/- DMDD6382_3d movie still

DMDD6382_3d movie still

DMDD6382 data

E14.5 -/- DMDD6381_3d movie still

DMDD6381_3d movie still

Ⓟ DMDD6381 data

E14.5 -/- DMDD6378_3d movie still

DMDD6378_3d movie still

Ⓟ DMDD6378 data

E14.5 -/- DMDD6377_3d movie still

DMDD6377_3d movie still

DMDD6377 data

E14.5 -/- DMDD6371_3d movie still

DMDD6371_3d movie still

DMDD6371 data

E14.5 +/+ DMDD6397_3d movie still

DMDD6397_3d movie still

Ⓟ DMDD6397 data

E14.5 +/+ DMDD6383_3d movie still

DMDD6383_3d movie still

Ⓟ DMDD6383 data

E14.5 +/+ DMDD6366_3d movie still

DMDD6366_3d movie still

Ⓟ DMDD6366 data

Ⓟ PLACENTA PHENOTYPES

EMBRYO PHENOTYPES

SAMPLE INFORMATION

DMDD6401 E14.5

Single page view for DMDD6401

Crim1^{<em1(IMPC)Wtsi>}/Crim1^{<em1(IMPC)Wtsi>}

DMDD6401_3d movie still

3D MOVIE

Opens in new window

VIEW HREM IMAGES

Opens stackviewer

DMDD6401_xz section

XZ MOVIE

Opens in new window

DMDD6401_yz section

YZ MOVIE

Opens in new window

DMDD6401_xy movie still

XY MOVIE

Opens in new window

The scale bar shown on the saggital image (links to XZ movie) represents 1 mm.

Placenta

ID	MP TERM
MP:0002169	no abnormal phenotype detected

Images

IMAGE TYPE	PROBE/ANTIGEN PROBE/ANTIGEN E-Cadherin (Cdh1) was used to demarcate syncytiotrophoblast in the placental labyrinth at E9.5, and to label parietal trophoblast giant cells. Isolectin BSI-B4 was used to highlight the placental labyrinth and the decidua. Tpbpa was used to mark spongiotrophoblast and glycogen cells. Yolk sacs were stained for E-Cadherin (green), Laminin (red) and DAPI. E-Cadherin labels the visceral yolk sac endoderm, Laminin labels the basement membrane between endoderm and mesoderm layers. ×	IMAGE
Hematoxylin and eosin	View placenta image at full resolution in a new window
In situ hybridisation	TpbpaView placenta image at full resolution in a new window
In situ hybridisation	TpbpaView placenta image at full resolution in a new window
Immunohistochemistry	E-CadherinView placenta image at full resolution in a new window
Immunohistochemistry	E-CadherinView placenta image at full resolution in a new window

PROPERTY	VALUE
Type	Mutant line
Viability of the line at P14	Lethal
Gene	Crim1
Allele	Crim1^{<em1(IMPC)Wtsi>}
Genotype	Crim1^{<em1(IMPC)Wtsi>}/Crim1^{<em1(IMPC)Wtsi>}
Strain	C57BL/6NTac
Stage	E14.5
Sex (morphological analysis)	Female
Sex (PCR analysis)	Not determined
Crown-rump length	9.9 mm
Somites	Not Determined
Fixation	Bouins
HREM voxel size	3 μm^<3>
DMDD ID	DMDD6401
Sanger ID	DABE15.1i
Order mouse	Order mouse from IMPC

DMDD6396 E14.5

Single page view for DMDD6396

Crim1^{<em1(IMPC)Wtsi>}/Crim1^{<em1(IMPC)Wtsi>}

DMDD6396_3d movie still

3D MOVIE

Opens in new window

VIEW HREM IMAGES

Opens stackviewer

DMDD6396_xz section

XZ MOVIE

Opens in new window

DMDD6396_yz section

YZ MOVIE

Opens in new window

DMDD6396_xy movie still

XY MOVIE

Opens in new window

The scale bar shown on the saggital image (links to XZ movie) represents 1 mm.

No placenta data is available for this embryo.

PROPERTY	VALUE
Type	Mutant line
Viability of the line at P14	Lethal
Gene	Crim1
Allele	Crim1^{<em1(IMPC)Wtsi>}
Genotype	Crim1^{<em1(IMPC)Wtsi>}/Crim1^{<em1(IMPC)Wtsi>}
Strain	C57BL/6NTac
Stage	E14.5
Sex (morphological analysis)	Female
Sex (PCR analysis)	Female
Crown-rump length	10.8 mm
Somites	Not Determined
Fixation	Bouins
HREM voxel size	3 μm^<3>
DMDD ID	DMDD6396
Sanger ID	DABE17.1i
Order mouse	Order mouse from IMPC

DMDD6388 E14.5

Single page view for DMDD6388

Crim1^{<em1(IMPC)Wtsi>}/Crim1^{<em1(IMPC)Wtsi>}

DMDD6388_3d movie still

3D MOVIE

Opens in new window

VIEW HREM IMAGES

Opens stackviewer

DMDD6388_xz section

XZ MOVIE

Opens in new window

DMDD6388_yz section

YZ MOVIE

Opens in new window

DMDD6388_xy movie still

XY MOVIE

Opens in new window

The scale bar shown on the saggital image (links to XZ movie) represents 1 mm.

Placenta

ID	MP TERM
MP:0002169	no abnormal phenotype detected

Images

IMAGE TYPE	PROBE/ANTIGEN PROBE/ANTIGEN E-Cadherin (Cdh1) was used to demarcate syncytiotrophoblast in the placental labyrinth at E9.5, and to label parietal trophoblast giant cells. Isolectin BSI-B4 was used to highlight the placental labyrinth and the decidua. Tpbpa was used to mark spongiotrophoblast and glycogen cells. Yolk sacs were stained for E-Cadherin (green), Laminin (red) and DAPI. E-Cadherin labels the visceral yolk sac endoderm, Laminin labels the basement membrane between endoderm and mesoderm layers. ×	IMAGE
Hematoxylin and eosin	View placenta image at full resolution in a new window
In situ hybridisation	TpbpaView placenta image at full resolution in a new window
In situ hybridisation	TpbpaView placenta image at full resolution in a new window
Immunohistochemistry	BSI-B4View placenta image at full resolution in a new window
Immunohistochemistry	E-CadherinView placenta image at full resolution in a new window
Immunohistochemistry	E-CadherinView placenta image at full resolution in a new window

PROPERTY	VALUE
Type	Mutant line
Viability of the line at P14	Lethal
Gene	Crim1
Allele	Crim1^{<em1(IMPC)Wtsi>}
Genotype	Crim1^{<em1(IMPC)Wtsi>}/Crim1^{<em1(IMPC)Wtsi>}
Strain	C57BL/6NTac
Stage	E14.5
Sex (morphological analysis)	Male
Sex (PCR analysis)	Not determined
Crown-rump length	10.5 mm
Somites	Not Determined
Fixation	Bouins
HREM voxel size	3 μm^<3>
DMDD ID	DMDD6388
Sanger ID	DABE17.1g
Order mouse	Order mouse from IMPC

DMDD6387 E14.5

Single page view for DMDD6387

Crim1^{<em1(IMPC)Wtsi>}/Crim1^{<em1(IMPC)Wtsi>}

DMDD6387_3d movie still

3D MOVIE

Opens in new window

VIEW HREM IMAGES

Opens stackviewer

DMDD6387_xz section

XZ MOVIE

Opens in new window

DMDD6387_yz section

YZ MOVIE

Opens in new window

DMDD6387_xy movie still

XY MOVIE

Opens in new window

The scale bar shown on the saggital image (links to XZ movie) represents 1 mm.

No placenta data is available for this embryo.

PROPERTY	VALUE
Type	Mutant line
Viability of the line at P14	Lethal
Gene	Crim1
Allele	Crim1^{<em1(IMPC)Wtsi>}
Genotype	Crim1^{<em1(IMPC)Wtsi>}/Crim1^{<em1(IMPC)Wtsi>}
Strain	C57BL/6NTac
Stage	E14.5
Sex (morphological analysis)	Male
Sex (PCR analysis)	Male
Crown-rump length	10.3 mm
Somites	Not Determined
Fixation	Bouins
HREM voxel size	3 μm^<3>
DMDD ID	DMDD6387
Sanger ID	DABE17.1e
Order mouse	Order mouse from IMPC

DMDD6384 E14.5

Single page view for DMDD6384

Crim1^{<em1(IMPC)Wtsi>}/Crim1^{<em1(IMPC)Wtsi>}

DMDD6384_3d movie still

3D MOVIE

Opens in new window

VIEW HREM IMAGES

Opens stackviewer

DMDD6384_xz section

XZ MOVIE

Opens in new window

DMDD6384_yz section

YZ MOVIE

Opens in new window

DMDD6384_xy movie still

XY MOVIE

Opens in new window

The scale bar shown on the saggital image (links to XZ movie) represents 1 mm.

Placenta

ID	MP TERM
MP:0002169	no abnormal phenotype detected

Images

IMAGE TYPE	PROBE/ANTIGEN PROBE/ANTIGEN E-Cadherin (Cdh1) was used to demarcate syncytiotrophoblast in the placental labyrinth at E9.5, and to label parietal trophoblast giant cells. Isolectin BSI-B4 was used to highlight the placental labyrinth and the decidua. Tpbpa was used to mark spongiotrophoblast and glycogen cells. Yolk sacs were stained for E-Cadherin (green), Laminin (red) and DAPI. E-Cadherin labels the visceral yolk sac endoderm, Laminin labels the basement membrane between endoderm and mesoderm layers. ×	IMAGE
Hematoxylin and eosin	View placenta image at full resolution in a new window
In situ hybridisation	TpbpaView placenta image at full resolution in a new window
In situ hybridisation	TpbpaView placenta image at full resolution in a new window
Immunohistochemistry	BSI-B4View placenta image at full resolution in a new window
Immunohistochemistry	BSI-B4View placenta image at full resolution in a new window
Immunohistochemistry	E-CadherinView placenta image at full resolution in a new window
Immunohistochemistry	E-CadherinView placenta image at full resolution in a new window

PROPERTY	VALUE
Type	Mutant line
Viability of the line at P14	Lethal
Gene	Crim1
Allele	Crim1^{<em1(IMPC)Wtsi>}
Genotype	Crim1^{<em1(IMPC)Wtsi>}/Crim1^{<em1(IMPC)Wtsi>}
Strain	C57BL/6NTac
Stage	E14.5 (Theiler stage TS23)
Sex (morphological analysis)	Male
Sex (PCR analysis)	Not determined
Crown-rump length	10.8 mm
Somites	Not Determined
Fixation	Bouins
HREM voxel size	2.55 μm^<3>
DMDD ID	DMDD6384
Sanger ID	DABE17.1d
Order mouse	Order mouse from IMPC

DMDD6382 E14.5

Single page view for DMDD6382

Crim1^{<em1(IMPC)Wtsi>}/Crim1^{<em1(IMPC)Wtsi>}

DMDD6382_3d movie still

3D MOVIE

Opens in new window

VIEW HREM IMAGES

Opens stackviewer

DMDD6382_xz section

XZ MOVIE

Opens in new window

DMDD6382_yz section

YZ MOVIE

Opens in new window

DMDD6382_xy movie still

XY MOVIE

Opens in new window

The scale bar shown on the saggital image (links to XZ movie) represents 1 mm.

No placenta data is available for this embryo.

PROPERTY	VALUE
Type	Mutant line
Viability of the line at P14	Lethal
Gene	Crim1
Allele	Crim1^{<em1(IMPC)Wtsi>}
Genotype	Crim1^{<em1(IMPC)Wtsi>}/Crim1^{<em1(IMPC)Wtsi>}
Strain	C57BL/6NTac
Stage	E14.5
Sex (morphological analysis)	Female
Sex (PCR analysis)	Female
Crown-rump length	9.7 mm
Somites	Not Determined
Fixation	Bouins
HREM voxel size	3 μm^<3>
DMDD ID	DMDD6382
Sanger ID	DABE15.1d
Order mouse	Order mouse from IMPC

DMDD6381 E14.5

Single page view for DMDD6381

Crim1^{<em1(IMPC)Wtsi>}/Crim1^{<em1(IMPC)Wtsi>}

DMDD6381_3d movie still

3D MOVIE

Opens in new window

VIEW HREM IMAGES

Opens stackviewer

DMDD6381_xz section

XZ MOVIE

Opens in new window

DMDD6381_yz section

YZ MOVIE

Opens in new window

DMDD6381_xy movie still

XY MOVIE

Opens in new window

The scale bar shown on the saggital image (links to XZ movie) represents 1 mm.

Placenta

ID	MP TERM
MP:0002169	no abnormal phenotype detected

Yolk sac

ID	MP TERM
MP:0002169	no abnormal phenotype detected

Images

IMAGE TYPE	PROBE/ANTIGEN PROBE/ANTIGEN E-Cadherin (Cdh1) was used to demarcate syncytiotrophoblast in the placental labyrinth at E9.5, and to label parietal trophoblast giant cells. Isolectin BSI-B4 was used to highlight the placental labyrinth and the decidua. Tpbpa was used to mark spongiotrophoblast and glycogen cells. Yolk sacs were stained for E-Cadherin (green), Laminin (red) and DAPI. E-Cadherin labels the visceral yolk sac endoderm, Laminin labels the basement membrane between endoderm and mesoderm layers. ×	IMAGE
Hematoxylin and eosin	View placenta image at full resolution in a new window
Yolk sac immunofluorescence	Green: E-Cadherin Red: Laminin Blue: DAPIView yolk sac image at full resolution in a new window
Yolk sac immunofluorescence	Green: E-Cadherin Red: Laminin Blue: DAPIView yolk sac image at full resolution in a new window

PROPERTY	VALUE
Type	Mutant line
Viability of the line at P14	Lethal
Gene	Crim1
Allele	Crim1^{<em1(IMPC)Wtsi>}
Genotype	Crim1^{<em1(IMPC)Wtsi>}/Crim1^{<em1(IMPC)Wtsi>}
Strain	C57BL/6NTac
Stage	E14.5
Sex (morphological analysis)	Male
Sex (PCR analysis)	Male
Crown-rump length	10.2 mm
Somites	Not Determined
Fixation	Bouins
HREM voxel size	3 μm^<3>
DMDD ID	DMDD6381
Sanger ID	DABE15.1a
Order mouse	Order mouse from IMPC

DMDD6378 E14.5

Single page view for DMDD6378

Crim1^{<em1(IMPC)Wtsi>}/Crim1^{<em1(IMPC)Wtsi>}

DMDD6378_3d movie still

3D MOVIE

Opens in new window

VIEW HREM IMAGES

Opens stackviewer

DMDD6378_xz section

XZ MOVIE

Opens in new window

DMDD6378_yz section

YZ MOVIE

Opens in new window

DMDD6378_xy movie still

XY MOVIE

Opens in new window

The scale bar shown on the saggital image (links to XZ movie) represents 1 mm.

Placenta

ID	MP TERM
MP:0002169	no abnormal phenotype detected

Yolk sac

ID	MP TERM
MP:0002169	no abnormal phenotype detected

Images

IMAGE TYPE	PROBE/ANTIGEN PROBE/ANTIGEN E-Cadherin (Cdh1) was used to demarcate syncytiotrophoblast in the placental labyrinth at E9.5, and to label parietal trophoblast giant cells. Isolectin BSI-B4 was used to highlight the placental labyrinth and the decidua. Tpbpa was used to mark spongiotrophoblast and glycogen cells. Yolk sacs were stained for E-Cadherin (green), Laminin (red) and DAPI. E-Cadherin labels the visceral yolk sac endoderm, Laminin labels the basement membrane between endoderm and mesoderm layers. ×	IMAGE
Hematoxylin and eosin	View placenta image at full resolution in a new window
Yolk sac immunofluorescence	Green: E-Cadherin Red: Laminin Blue: DAPIView yolk sac image at full resolution in a new window
Yolk sac immunofluorescence	Green: E-Cadherin Red: Laminin Blue: DAPIView yolk sac image at full resolution in a new window

PROPERTY	VALUE
Type	Mutant line
Viability of the line at P14	Lethal
Gene	Crim1
Allele	Crim1^{<em1(IMPC)Wtsi>}
Genotype	Crim1^{<em1(IMPC)Wtsi>}/Crim1^{<em1(IMPC)Wtsi>}
Strain	C57BL/6NTac
Stage	E14.5 (Theiler stage TS23)
Sex (morphological analysis)	Not determined
Sex (PCR analysis)	Not determined
Comments on sex	Potential sex reversal
Crown-rump length	9.6 mm
Somites	Not Determined
Fixation	Bouins
HREM voxel size	2.61 μm^<3>
DMDD ID	DMDD6378
Sanger ID	DABE13.1f
Order mouse	Order mouse from IMPC

DMDD6377 E14.5

Single page view for DMDD6377

Crim1^{<em1(IMPC)Wtsi>}/Crim1^{<em1(IMPC)Wtsi>}

DMDD6377_3d movie still

3D MOVIE

Opens in new window

VIEW HREM IMAGES

Opens stackviewer

DMDD6377_xz section

XZ MOVIE

Opens in new window

DMDD6377_yz section

YZ MOVIE

Opens in new window

DMDD6377_xy movie still

XY MOVIE

Opens in new window

The scale bar shown on the saggital image (links to XZ movie) represents 1 mm.

No placenta data is available for this embryo.

PROPERTY	VALUE
Type	Mutant line
Viability of the line at P14	Lethal
Gene	Crim1
Allele	Crim1^{<em1(IMPC)Wtsi>}
Genotype	Crim1^{<em1(IMPC)Wtsi>}/Crim1^{<em1(IMPC)Wtsi>}
Strain	C57BL/6NTac
Stage	E14.5
Sex (morphological analysis)	Female
Sex (PCR analysis)	Not determined
Crown-rump length	10.7 mm
Somites	Not Determined
Fixation	Bouins
HREM voxel size	3 μm^<3>
DMDD ID	DMDD6377
Sanger ID	DABE12.1b
Order mouse	Order mouse from IMPC

DMDD6371 E14.5

Single page view for DMDD6371

Crim1^{<em1(IMPC)Wtsi>}/Crim1^{<em1(IMPC)Wtsi>}

DMDD6371_3d movie still

3D MOVIE

Opens in new window

VIEW HREM IMAGES

Opens stackviewer

DMDD6371_xz section

XZ MOVIE

Opens in new window

DMDD6371_yz section

YZ MOVIE

Opens in new window

DMDD6371_xy movie still

XY MOVIE

Opens in new window

The scale bar shown on the saggital image (links to XZ movie) represents 1 mm.

No placenta data is available for this embryo.

PROPERTY	VALUE
Type	Mutant line
Viability of the line at P14	Lethal
Gene	Crim1
Allele	Crim1^{<em1(IMPC)Wtsi>}
Genotype	Crim1^{<em1(IMPC)Wtsi>}/Crim1^{<em1(IMPC)Wtsi>}
Strain	C57BL/6NTac
Stage	E14.5 (Theiler stage TS23)
Sex (morphological analysis)	Male
Sex (PCR analysis)	Male
Crown-rump length	10.7 mm
Somites	Not Determined
Fixation	Bouins
HREM voxel size	2.61 μm^<3>
DMDD ID	DMDD6371
Sanger ID	DABE17.1f
Order mouse	Order mouse from IMPC

DMDD6397 E14.5

Single page view for DMDD6397

+/+

DMDD6397_3d movie still

3D MOVIE

Opens in new window

VIEW HREM IMAGES

Opens stackviewer

DMDD6397_xz section

XZ MOVIE

Opens in new window

DMDD6397_yz section

YZ MOVIE

Opens in new window

DMDD6397_xy movie still

XY MOVIE

Opens in new window

The scale bar shown on the saggital image (links to XZ movie) represents 1 mm.

Placenta

ID	MP TERM
MP:0002169	no abnormal phenotype detected

Images

IMAGE TYPE	PROBE/ANTIGEN PROBE/ANTIGEN E-Cadherin (Cdh1) was used to demarcate syncytiotrophoblast in the placental labyrinth at E9.5, and to label parietal trophoblast giant cells. Isolectin BSI-B4 was used to highlight the placental labyrinth and the decidua. Tpbpa was used to mark spongiotrophoblast and glycogen cells. Yolk sacs were stained for E-Cadherin (green), Laminin (red) and DAPI. E-Cadherin labels the visceral yolk sac endoderm, Laminin labels the basement membrane between endoderm and mesoderm layers. ×	IMAGE
Hematoxylin and eosin	View placenta image at full resolution in a new window
In situ hybridisation	TpbpaView placenta image at full resolution in a new window
Immunohistochemistry	BSI-B4View placenta image at full resolution in a new window
Immunohistochemistry	BSI-B4View placenta image at full resolution in a new window
Immunohistochemistry	E-CadherinView placenta image at full resolution in a new window

PROPERTY	VALUE
Type	Mutant line
Viability of the line at P14	Lethal
Gene	Crim1
Allele	Crim1^{<em1(IMPC)Wtsi>}
Genotype	+/+
Strain	C57BL/6NTac
Stage	E14.5 (Theiler stage TS23)
Sex (morphological analysis)	Male
Sex (PCR analysis)	Not determined
Crown-rump length	12.0 mm
Somites	Not Determined
Fixation	Bouins
HREM voxel size	2.61 μm^<3>
DMDD ID	DMDD6397
Sanger ID	DABE17.1j
Order mouse	Order mouse from IMPC

DMDD6383 E14.5

Single page view for DMDD6383

+/+

DMDD6383_3d movie still

3D MOVIE

Opens in new window

VIEW HREM IMAGES

Opens stackviewer

DMDD6383_xz section

XZ MOVIE

Opens in new window

DMDD6383_yz section

YZ MOVIE

Opens in new window

DMDD6383_xy movie still

XY MOVIE

Opens in new window

The scale bar shown on the saggital image (links to XZ movie) represents 1 mm.

Placenta

ID	MP TERM
MP:0002169	no abnormal phenotype detected

Images

IMAGE TYPE	PROBE/ANTIGEN PROBE/ANTIGEN E-Cadherin (Cdh1) was used to demarcate syncytiotrophoblast in the placental labyrinth at E9.5, and to label parietal trophoblast giant cells. Isolectin BSI-B4 was used to highlight the placental labyrinth and the decidua. Tpbpa was used to mark spongiotrophoblast and glycogen cells. Yolk sacs were stained for E-Cadherin (green), Laminin (red) and DAPI. E-Cadherin labels the visceral yolk sac endoderm, Laminin labels the basement membrane between endoderm and mesoderm layers. ×	IMAGE
Hematoxylin and eosin	View placenta image at full resolution in a new window
In situ hybridisation	TpbpaView placenta image at full resolution in a new window
Immunohistochemistry	BSI-B4View placenta image at full resolution in a new window
Immunohistochemistry	BSI-B4View placenta image at full resolution in a new window
Immunohistochemistry	E-CadherinView placenta image at full resolution in a new window
Immunohistochemistry	E-CadherinView placenta image at full resolution in a new window

PROPERTY	VALUE
Type	Mutant line
Viability of the line at P14	Lethal
Gene	Crim1
Allele	Crim1^{<em1(IMPC)Wtsi>}
Genotype	+/+
Strain	C57BL/6NTac
Stage	E14.5 (Theiler stage TS23-)
Sex (morphological analysis)	Male
Sex (PCR analysis)	Not determined
Crown-rump length	10.7 mm
Somites	Not Determined
Fixation	Bouins
HREM voxel size	2.61 μm^<3>
DMDD ID	DMDD6383
Sanger ID	DABE17.1c
Order mouse	Order mouse from IMPC

DMDD6366 E14.5

Single page view for DMDD6366

+/+

DMDD6366_3d movie still

3D MOVIE

Opens in new window

VIEW HREM IMAGES

Opens stackviewer

DMDD6366_xz section

XZ MOVIE

Opens in new window

DMDD6366_yz section

YZ MOVIE

Opens in new window

DMDD6366_xy movie still

XY MOVIE

Opens in new window

The scale bar shown on the saggital image (links to XZ movie) represents 1 mm.

Placenta

ID	MP TERM
MP:0002169	no abnormal phenotype detected

Images

IMAGE TYPE	PROBE/ANTIGEN PROBE/ANTIGEN E-Cadherin (Cdh1) was used to demarcate syncytiotrophoblast in the placental labyrinth at E9.5, and to label parietal trophoblast giant cells. Isolectin BSI-B4 was used to highlight the placental labyrinth and the decidua. Tpbpa was used to mark spongiotrophoblast and glycogen cells. Yolk sacs were stained for E-Cadherin (green), Laminin (red) and DAPI. E-Cadherin labels the visceral yolk sac endoderm, Laminin labels the basement membrane between endoderm and mesoderm layers. ×	IMAGE
Hematoxylin and eosin	View placenta image at full resolution in a new window
In situ hybridisation	TpbpaView placenta image at full resolution in a new window
Immunohistochemistry	BSI-B4View placenta image at full resolution in a new window
Immunohistochemistry	E-CadherinView placenta image at full resolution in a new window
Immunohistochemistry	E-CadherinView placenta image at full resolution in a new window

PROPERTY	VALUE
Type	Mutant line
Viability of the line at P14	Lethal
Gene	Crim1
Allele	Crim1^{<em1(IMPC)Wtsi>}
Genotype	+/+
Strain	C57BL/6NTac
Stage	E14.5 (Theiler stage TS23-)
Sex (morphological analysis)	Female
Sex (PCR analysis)	Not determined
Crown-rump length	9.8 mm
Somites	Not Determined
Fixation	Bouins
HREM voxel size	2.55 μm^<3>
DMDD ID	DMDD6366
Sanger ID	DABE15.1g
Order mouse	Order mouse from IMPC

FIRST TIME HERE?

We recommend you take the 30 second page tour which provides an overview of the page functionality.
1/7 CAROUSEL

This shows all the embryos available for the line.
2/7 LINE SUMMARY

Phenotype data for the LINE can be viewed by clicking this button.
3/7 EMBRYO DATA

The lower part of the page shows all the data available for the sample highlighted in red.
4/7 DATA TABS

The tabs show different types of data collected for each sample.
5/7 PLACENTA PHENOTYPES ICONS

Availability of placental phenotype data is indicated by Ⓟ in the carousel above.
6/7 EMBRYO PHENOTYPES ICONS

Availability of embryo phenotype data is indicated by in the carousel above.
7/7 TOUR END

That's the end of the page tour. You can retake it anytime by clicking on the help icon.

30 SECOND PAGE TOUR

Provides an overview of line page functionality.
1/7 CAROUSEL

This shows all the embryos available for the line.
2/7 LINE SUMMARY

Phenotype data for the LINE can be viewed by clicking this button.
3/7 EMBRYO DATA

The lower part of the page shows all the data available for the sample highlighted in red.
4/7 DATA TABS

The tabs show different types of data collected for each sample.
5/7 PLACENTA PHENOTYPES ICON

Availability of placental phenotype data is indicated by Ⓟ in the carousel above.
6/7 EMBRYO PHENOTYPES ICON

Availability of embryo phenotype data is indicated by in the carousel above.
7/7 TOUR END

That's the end of the page tour. You can retake it anytime by clicking on the help icon.